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[一种来自苏木心材的新黄酮类化合物]

[A new flavonoid from heartwood of Caesalpinia sappan].

作者信息

Shu Shi-Hui, Han Jing-Lan, Du Guan-Hua, Qin Hai-Lin

机构信息

Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Key Laboratory of Bioactive Substances and Resources of Chinese Herbal Medicine, Ministry of Education, Beijing 100050, China.

出版信息

Zhongguo Zhong Yao Za Zhi. 2008 Apr;33(8):903-5.

Abstract

OBJECTIVE

To seek for new active components from Caesalpinia sappan.

METHOD

The chemical constituents were isolated and identified by means of chromatographic and spectroscopic technologies methods.

RESULT

Nine compounds were isolated, and their structures were identified as 3, 8-dihydroxy4, 10-dimethoxy-7-oxo-[2] benzopyrano[4,3-b] benzopyran (1), 3-deoxysappanchalcone (2), sappanchalcone (3), 3-deoxysappanone B (4), rhamnetin (5), protosappanin C (6), 3, 7-dihydroxy-chroman-4-one (7), dimethyl adipate (8), daucosterin (9).

CONCLUSION

Compound 1 was a new compound, and compounds 7, 8 were isolated from this plant for the first time.

摘要

目的

从苏木中寻找新的活性成分。

方法

采用色谱和光谱技术方法对化学成分进行分离和鉴定。

结果

分离得到9个化合物,其结构分别鉴定为3,8-二羟基-4,10-二甲氧基-7-氧代-[2]苯并吡喃并[4,3-b]苯并吡喃(1)、3-脱氧苏木查耳酮(2)、苏木查耳酮(3)、3-脱氧苏木酮B(4)、鼠李素(5)、原苏木素C(6)、3,7-二羟基色满-4-酮(7)、己二酸二甲酯(8)、胡萝卜苷(9)。

结论

化合物1为新化合物,化合物7、8为首次从该植物中分离得到。

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