Cai Shao-Qing, Wang Rufeng, Yang Xiuwei, Shang Mingying, Ma Chaomei, Shoyama Yukihiro
The State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing 100083, PR China.
Chem Biodivers. 2006 Mar;3(3):343-8. doi: 10.1002/cbdv.200690037.
Two new flavonoid-type C-glycosides, trollisin I (= (1S)-1,5-anhydro-1-[2-(3,4-dihydroxyphenyl)-5-hydroxy-7-methoxy-4-oxo-4H-[1]benzopyran-8-yl]-2-O-(2-methylbutanoyl)-D-glucitol; 1) and its 2-O-benzoyl congener trollisin II (2), were isolated from Trollius chinensis Bunge, together with the two known compounds 2''-O-(2'''-methylbutanoyl)isoswertisin (3) and vitexin galactoside (4). All compounds were identified by HR-ESI-MS and in-depth NMR-spectroscopic analyses. In antiviral assays, compound 3 was found to be moderately active towards influenza virus A.
从金莲花（Trollius chinensis Bunge）中分离出两种新的黄酮类C-糖苷，金莲花苷I（=(1S)-1,5-脱水-1-[2-(3,4-二羟基苯基)-5-羟基-7-甲氧基-4-氧代-4H-[1]苯并吡喃-8-基]-2-O-(2-甲基丁酰基)-D-葡萄糖醇；1）及其2-O-苯甲酰基类似物金莲花苷II（2），以及两种已知化合物2''-O-(2'''-甲基丁酰基)异荭草苷（3）和牡荆素半乳糖苷（4）。所有化合物均通过高分辨电喷雾电离质谱（HR-ESI-MS）和深入的核磁共振光谱分析进行鉴定。在抗病毒试验中，发现化合物3对甲型流感病毒具有中等活性。
