Lido Alessandro Vito, Kitamura Satoshi, Oliveira José Inácio, Lucca Sérgio Roberto de, Azevedo Valmir Antonio Zulian de, Bagatin Ericson
Departamento de Medicina Preventiva e Social, Faculdade de Ciências Médicas, Universidade Estadual de Campinas, Campinas, SP, Brasil.
J Bras Pneumol. 2008 Jun;34(6):367-72. doi: 10.1590/s1806-37132008000600006.
To develop and consolidate a comprehensive database on the occurrence of pneumoconioses in an industrialized region of Brazil, with a special focus on the activities most frequently related to these diseases.
A retrospective, observational study was conducted in order to gather data on cases of pneumoconioses treated at the outpatient clinic of the State University at Campinas Hospital das Clínicas between 1978 and 2003. Individuals diagnosed with pneumoconiosis, based on their occupational history and on chest X-ray findings of abnormalities consistent with interstitial lung disease involving the parenchyma, in accordance with the 1980 and 2000 recommendations of the International Labour Organization, were included in the study.
A total of 1147 cases of pneumoconiosis were identified (1075 in males and 72 in females): 1061 cases of silicosis (92.5%); 51 cases of mixed-dust pneumoconiosis (4.45%); 15 cases of asbestosis (1.31%); 13 cases of phosphate rock-related pneumoconiosis (1.13%); and 7 cases of other types of pneumoconiosis (0.6%), including those related to exposure to coal, graphite and hard metals. The most common chest X-ray findings were 1/0, 1/1 or 1/2 profusion and small regular opacities (p, q or r), although 192 patients (16.74%) presented large opacities. There has been a substantial decline in the occurrence of the disease since the 1990s, and the duration of exposure was typically shorter than that observed in a study conducted in the United States.
Our findings have been compiled into a comprehensive database for the investigation of pneumoconiosis in an industrialized area of Brazil. These data make it possible to conduct follow-up studies and develop health policies related to occupational respiratory disorders.
建立并巩固巴西一个工业化地区尘肺病发病情况的综合数据库，特别关注与这些疾病最常相关的活动。
开展一项回顾性观察研究，以收集1978年至2003年期间在坎皮纳斯州立大学临床医院门诊治疗的尘肺病病例数据。根据国际劳工组织1980年和2000年的建议，基于职业史和胸部X线检查发现与累及实质的间质性肺病相符的异常情况而被诊断为尘肺病的个体被纳入研究。
共确定1147例尘肺病病例（男性1075例，女性72例）：矽肺1061例（92.5%）；混合性粉尘尘肺51例（4.45%）；石棉肺15例（1.31%）；磷灰石相关尘肺13例（1.13%）；其他类型尘肺7例（0.6%），包括与接触煤、石墨和硬质金属相关的病例。胸部X线最常见的表现为1/0、1/1或1/2的密集度和小的规则性阴影（p、q或r），不过192例患者（16.74%）出现大阴影。自20世纪90年代以来，该病的发病率大幅下降，暴露时长通常短于在美国进行的一项研究中观察到的情况。
我们的研究结果已编入巴西一个工业化地区尘肺病调查的综合数据库。这些数据使得开展随访研究并制定与职业性呼吸系统疾病相关的卫生政策成为可能。
