一株中国超强毒传染性法氏囊病病毒的序列及系统发育分析
Sequence and phylogenetic analysis of a Chinese very virulent infectious bursal disease virus.
作者信息
Xia R X, Wang H Y, Huang G M, Zhang M F
机构信息
Laboratory for Animal Molecular Virology, Department of Molecular Biology and Biochemistry, College of Biological Science, China Agricultural University, 100094 Beijing, China.
出版信息
Arch Virol. 2008;153(9):1725-9. doi: 10.1007/s00705-008-0140-8. Epub 2008 Jul 12.
The complete genome sequence of a Chinese very virulent infectious bursal disease virus (vvIBDV) strain, Harbin-1, was determined. Based on the sequence analysis, the molecular characteristics and potential virulence determinants and origin of vvIBDV strains were identified. Phylogenetic analysis indicated that a reassortment and/or recombination event may have occurred in the emergence of Chinese vvIBDV strains.
测定了一株中国超强毒传染性法氏囊病病毒（vvIBDV）哈尔滨-1株的全基因组序列。基于序列分析，鉴定了vvIBDV毒株的分子特征、潜在毒力决定因素及起源。系统发育分析表明，中国vvIBDV毒株的出现可能发生了重配和/或重组事件。
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