Wheeldon John A, Stemper Brian D, Yoganandan Narayan, Pintar Frank A
Department of Neurosurgery, Medical College of Wisconsin, 9200 West Wisconsin Avenue, Milwaukee, WI 53226, USA.
Ann Biomed Eng. 2008 Sep;36(9):1458-69. doi: 10.1007/s10439-008-9534-8. Epub 2008 Jul 12.
A Finite Element Model (FEM) of the young adult human cervical spine has been developed as a first step in studying the process of spondylotic degeneration. The model was developed using normal geometry and material properties for the lower cervical spine. The model used a three-zone composite disc annulus to reflect the different material properties of the anterior, posterior, and lateral regions of the annulus. Nonlinear ligaments were implemented with a toe region to help the model achieve greater flexibility at low loads. The model was validated against experimental data for normal, nondegenerated cervical spines tested in flexion and extension, right and left lateral bending, and right and left axial rotation at loads of 0.33, 0.5, 1.0, 1.5, and 2.0 Nm. The model was within in vitro experimental standard deviation corridors 100% of the load range for right and left lateral bending. The model was within 80% of the load response corridors for extension and flexion with a deviation <0.3 degrees from the SD corridors. For axial rotation, the model was within 70% of the SD corridors for left axial rotation within 83% of right axial rotation responses. The deviation from SD corridors for axial rotation was generally <0.2 degrees.
作为研究脊柱退变过程的第一步，已构建了年轻成人人类颈椎的有限元模型（FEM）。该模型采用下颈椎的正常几何形状和材料属性构建。模型使用三区复合椎间盘环来反映椎间盘环前、后和外侧区域不同的材料属性。非线性韧带采用趾区来帮助模型在低负荷下实现更大的灵活性。该模型针对在0.33、0.5、1.0、1.5和2.0 Nm负荷下进行屈伸、左右侧屈以及左右轴向旋转测试的正常、未退变颈椎的实验数据进行了验证。对于左右侧屈，模型在体外实验标准差范围内的负荷范围占比100%。对于屈伸，模型在负荷响应范围内占比80%，与标准差范围的偏差<0.3度。对于轴向旋转，模型在左侧轴向旋转的标准差范围内占比70%，在右侧轴向旋转响应的83%范围内。轴向旋转与标准差范围的偏差通常<0.2度。
