Fine E J
Department of Nuclear Medicine, Albert Einstein College of Medicine, Bronx, NY 10461.
Semin Nucl Med. 1991 Apr;21(2):116-27. doi: 10.1016/s0001-2998(05)80049-2.
Physiological and pharmacological intervention for the purpose of determining organ functional reserve is a familiar concept in medical testing and in nuclear medicine. Nephrourologic applications include established procedures such as diuretic scintigraphy for determination of urinary outflow obstruction and captopril scintigraphy for determination of renovascular hypertension. Subtle renal dysfunction may exist among some individuals with essential hypertension, induced by provocative exercise renography, and not observed at rest. The strength of nuclear medicine resides in its ability to assess disorders of organ function for the diagnostic, prognostic, or pathophysiological information provided. Nephrourologic interventions are reviewed with an emphasis on the functional changes caused by the intervention.
为确定器官功能储备而进行的生理和药理学干预在医学检测和核医学中是一个常见的概念。肾脏泌尿系统应用包括一些既定程序,如用于确定尿路梗阻的利尿肾动态显像和用于确定肾血管性高血压的卡托普利肾动态显像。在一些原发性高血压患者中,通过激发运动肾图检查可能会发现轻微的肾功能不全,而在静息状态下则未观察到。核医学的优势在于其能够评估器官功能障碍,以提供诊断、预后或病理生理信息。本文对肾脏泌尿系统干预进行了综述,重点关注干预引起的功能变化。