Larkin M F
New South Wales State Cancer Council, Special Unit, Prince of Wales Hospital, Randwick, NSW, Australia.
J Natl Cancer Inst. 1967 Oct;39(4):633-8.
The distribution of haptoglobin types in 526 cancerous and 430 noncancerous subjects is presented. The frequency of haptoglobin 1 gene, in females, ranged sequentially from 0.264 in patients with cancer of the cervix, uterus, and ovary, through melanoma, breast cancer, cancer of the colon, to 0.467 in reticuloses. This was supported by statistically significant differences observed between some groups of cancer patients and normal controls. A different haptoglobin 1 gene frequency was found for male cancer patients.
本文呈现了526名癌症患者和430名非癌症患者中触珠蛋白类型的分布情况。在女性中，触珠蛋白1基因的频率依次变化，从子宫颈癌、子宫癌和卵巢癌患者中的0.264，到黑色素瘤、乳腺癌、结肠癌患者中的频率，再到网状细胞增多症患者中的0.467。这一点得到了部分癌症患者组与正常对照组之间观察到的具有统计学意义的差异的支持。在男性癌症患者中发现了不同的触珠蛋白1基因频率。
