Bartel U, Elling D, Geserick G
Zentralbl Gynakol. 1985;107(24):1492-5.
The haptoglobin types were determined by starch gel electrophoresis in 246 women with benigne and malignant gynaecologic neoplasms or breast tumors. There was a higher Hp1-gene frequency in all investigated patients compared with the normal distribution caused by a significant increase of Hp 1-1 type and a lower rate of Hp 2-2 type. The Hp 2-2 type was lower in the cases with benigne and malignant neoplasms of cervix and cervical carcinomas. The Hp 1-1 type was higher in the group of mamma tumors. A connection between these findings and the immune systems is discussed.
通过淀粉凝胶电泳法对246名患有良性和恶性妇科肿瘤或乳腺肿瘤的女性进行触珠蛋白类型测定。与正常分布相比，所有受调查患者的Hp1基因频率更高，这是由于Hp 1-1型显著增加以及Hp 2-2型比例降低所致。在宫颈良性和恶性肿瘤及宫颈癌病例中，Hp 2-2型较低。在乳腺肿瘤组中，Hp 1-1型较高。讨论了这些发现与免疫系统之间的联系。
