Wang Yi-Xiang
Department of Radiology, The Chinese University of Hong Kong, Hong Kong, China.
Lab Anim. 2008 Jul;42(3):246-64. doi: 10.1258/la.2007.06041e.
Recent technical developments in high-field magnetic resonance (MR) scanners, improvement in radio frequency coil design and gradient performance along with the development of efficient pulse sequences and new methods of enhancing contrast have made high-quality imaging of animal arthritis models feasible. MR can provide high-resolution structural information about the osteoarthritic changes in animal models, and also information about the biophysical properties of cartilage. This paper reviews the MR techniques available for animal knee imaging, and the various MR-derived readouts of knee osteoarthritis in animal models. Pitfalls in interpreting animal joint anatomy and joint composition are highlighted.
高场磁共振（MR）扫描仪的最新技术发展、射频线圈设计和梯度性能的改进，以及高效脉冲序列的开发和增强对比度的新方法，使得对动物关节炎模型进行高质量成像成为可能。磁共振成像可以提供关于动物模型骨关节炎变化的高分辨率结构信息，以及软骨生物物理特性的信息。本文综述了用于动物膝关节成像的磁共振技术，以及动物模型中膝关节骨关节炎的各种磁共振衍生读数。文中强调了解释动物关节解剖结构和关节组成时的注意事项。
