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氯氰菊酯和多菌灵在细胞周期特定阶段的应用以评估大麦体细胞的遗传毒性

Cell cycle stage specific application of cypermethrin and carbendazim to assess the genotoxicity in somatic cells of Hordeum vulgare L.

作者信息

Singh Parul, Srivastava Anjil Kumar, Singh Ashok Kumar

机构信息

Genotoxic Lab, Department of Botany, Faculty of Sciences, Udai Pratap Autonomous College, Varanasi 221002, India.

出版信息

Bull Environ Contam Toxicol. 2008 Sep;81(3):258-61. doi: 10.1007/s00128-008-9469-7. Epub 2008 Jul 15.

Abstract

In this study, the genotoxicity of commonly used insecticide cypermethrin and fungicide carbendazim were examined on root meristem cells of Hordeum vulgare L. Cypermethrin and carbendazim were applied with concentrations of 0.05%, 0.1% and 0.5% at different presoaking durations of 7 h, 17 h and 27 h which falls into G(1), S and G(2) phases of cell cycle, respectively. The cytogenetic studies of the root meristem cells of Hordeum vulgare L. showed that S phase of the cell cycle was more sensitive in comparison to other phases of cell cycle.

摘要

在本研究中,检测了常用杀虫剂氯氰菊酯和杀菌剂多菌灵对大麦根分生组织细胞的遗传毒性。氯氰菊酯和多菌灵分别以0.05%、0.1%和0.5%的浓度在7小时、17小时和27小时的不同预浸泡时间下施用,这三个时间分别对应细胞周期的G(1)、S和G(2)期。对大麦根分生组织细胞的细胞遗传学研究表明,与细胞周期的其他阶段相比,细胞周期的S期更敏感。

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