来自百部（Stemona cochinchinensis）根中的双苯并吡喃类化合物和生物碱。

Bisbenzopyrans and alkaloids from the roots of Stemona cochinchinensis.

作者信息

Dien Pham-Huu, Lin Li-Gin, Tang Chun-Ping, Ke Chang-Qiang, Ye Yang

机构信息

Faculty of Chemistry, Department of Organic Chemistry, Hanoi National University of Education, Caugiay District, Hanoi, Vietnam.

出版信息

Nat Prod Res. 2008;22(10):915-20. doi: 10.1080/14786410701642771.

DOI:10.1080/14786410701642771

PMID:18626828

Abstract

Two new bisbenzopyrans, namely 3,3'-bis(3,4-dihydro-4-hydroxy-6,8-dimethoxy-2H-1-benzopyran) (1), and 8'-methoxy-3,3'-bis(3,4-dihydro-4-hydroxy-6-methoxy-2H-1-benzopyran) (2), together with known 3,3'-bis(3,4-dihydro-4-hydroxy-6-methoxy-2H-1-benzopyran) (3), as well as three known pyrido[1,2-alpha]azapine alkaloids, stemokerrin (4), oxystemokerrin (5) and oxystemokerrin-N-oxide (6), were isolated and identified from the roots of Stemona cochinchinensis. The structures of these compounds were elucidated by 1D- and 2D-NMR spectra and other spectroscopic studies.

摘要

从广西百部属植物的根中分离并鉴定出两种新的双苯并吡喃，即3,3'-双(3,4-二氢-4-羟基-6,8-二甲氧基-2H-1-苯并吡喃)(1)和8'-甲氧基-3,3'-双(3,4-二氢-4-羟基-6-甲氧基-2H-1-苯并吡喃)(2)，以及已知的3,3'-双(3,4-二氢-4-羟基-6-甲氧基-2H-1-苯并吡喃)(3)，还有三种已知的吡啶并[1,2-α]氮杂蒽生物碱，即百部定(4)、氧化百部定(5)和氧化百部定-N-氧化物(6)。这些化合物的结构通过一维和二维核磁共振谱以及其他光谱研究得以阐明。