Boonchai Waranya, Iamtharachai Pacharee, Sunthonpalin Patcharee
Department of Dermatology, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Dermatitis. 2008 May-Jun;19(3):142-5.
Contact dermatitis is a universal condition. Patch testing is an effective diagnostic tool for clinically suspected allergic contact dermatitis. Previous studies have shown that the prevalence of specific allergens varies by geographic area.
To determine the relative frequency of positive reactions to different sensitizers in Thai patients with clinically suspected contact dermatitis.
The results of patch tests performed from January 1, 2004, to December 31, 2006, at the Siriraj Hospital Contact Dermatitis Clinic were analyzed. A total of 323 consecutive patients (83% women and 17% men, with mean age of 39 years) were patch-tested with the total number of allergens used from both European standard patch test series and International patch test series was 26.
The most frequent allergen was potassium dichromate (27%), followed by nickel sulfate (26.6%), fragrance mix (20.7%), and cobalt chloride (16.4%).
We compared the results with published findings in Asian-Pacific populations to identify geographic cultural differences in the prevalence of the allergens. The findings of the present study are able to identify the set of prominent local allergens for better revision of the standard patch test to local needs.
接触性皮炎是一种常见病症。斑贴试验是临床疑似过敏性接触性皮炎的有效诊断工具。既往研究表明，特定变应原的患病率因地理区域而异。
确定泰国临床疑似接触性皮炎患者对不同致敏剂阳性反应的相对频率。
分析了2004年1月1日至2006年12月31日在诗里拉吉医院接触性皮炎诊所进行的斑贴试验结果。共有323例连续患者（83%为女性，17%为男性，平均年龄39岁）接受了斑贴试验，使用的变应原总数来自欧洲标准斑贴试验系列和国际斑贴试验系列，共26种。
最常见的变应原是重铬酸钾（27%），其次是硫酸镍（26.6%）、香料混合物（20.7%）和氯化钴（16.4%）。
我们将结果与亚太人群已发表的研究结果进行比较，以确定变应原患病率的地理文化差异。本研究结果能够确定一组突出的当地变应原，以便更好地根据当地需求修订标准斑贴试验。
