Mitrani A A, Gonzalez M L, O'Connell M T, Guerra J, Harwood R B, Gardner L B
Department of Medicine, University of Miami School of Medicine, Florida 33101.
Am J Surg. 1991 Jun;161(6):646-50. doi: 10.1016/0002-9610(91)91248-h.
Venography is the current standard for the diagnosis of deep vein thrombosis (DVT). Noninvasive tests have differing sensitivity and specificity, are technically demanding, and may be subject to variability in interpretation. Light reflection rheography (LRR) is a noninvasive method utilizing light-emitting diodes and a sensor to measure light reflected from the skin surface. The intensity of reflected light establishes a graphic pattern that indirectly quantifies parameters of venous function by measuring changes in the microcirculation. Seventy-two patients who underwent contrast venography at our institution were also evaluated with LRR. Twenty-four patients were found to have DVT as demonstrated by venography. Of these, 23 also had DVT detected by LRR. No evidence of thrombus was seen in 45 patients studied by venography; in this group, 35 had normal venous emptying indicated by LRR. Using LRR, a sensitivity of 96% was achieved in the evaluation of clinically suspected DVT. This sensitivity is comparable with other noninvasive tests. In addition, LRR is easy to operate, portable, inexpensive, and not technically demanding. Further investigation is needed to confirm these data and further define the role of LRR in the evaluation of clinically suspected DVT.
静脉造影术是目前诊断深静脉血栓形成（DVT）的标准方法。非侵入性检查的敏感性和特异性各不相同，技术要求高，且在解读上可能存在差异。光反射血流描记术（LRR）是一种利用发光二极管和传感器测量从皮肤表面反射的光的非侵入性方法。反射光的强度形成一种图形模式，通过测量微循环的变化间接量化静脉功能参数。在我们机构接受造影剂静脉造影的72例患者也接受了LRR评估。静脉造影显示24例患者患有DVT。其中，23例通过LRR也检测出患有DVT。静脉造影检查的45例患者未发现血栓迹象；在该组中，35例LRR显示静脉排空正常。使用LRR评估临床疑似DVT时，敏感性达到96%。该敏感性与其他非侵入性检查相当。此外，LRR易于操作、便携、价格低廉且技术要求不高。需要进一步研究以证实这些数据，并进一步明确LRR在临床疑似DVT评估中的作用。
