Rai Sumit, Chakravarti Anita, Matlani Monika, Bhalla Preena, Aggarwal Vijay, Singh N, Diwan R
Department of Microbiology, MAMC, New Delhi, India.
Trop Doct. 2008 Jul;38(3):175-7. doi: 10.1258/td.2007.070229.
There are outbreaks of dengue every year in India. They vary in the predominant serotype involved, clinical features and predominant laboratory findings. This study of the 2006 outbreak in Delhi highlights clinical features and laboratory parameters of dengue cases and compares the clinical features among the adult and paediatric age groups. The 2006 outbreak had higher bleeding manifestations and a greater involvement of the adult male population than in previous outbreaks. No correlation was observed between platelet count and different bleeding manifestations until they dropped <20,000 per microL. Few patients developed a florid picture before seroconversion, highlighting a greater stress on the haematological rather than immunological profile of such patients. Atypical symptoms, such as diarrhoea, menorrhagia and seizures were often the presenting complaints rather than the typical clinical features of dengue.
印度每年都会爆发登革热疫情。这些疫情在涉及的主要血清型、临床特征和主要实验室检查结果方面存在差异。这项对2006年德里疫情的研究突出了登革热病例的临床特征和实验室参数，并比较了成人和儿童年龄组的临床特征。与以往疫情相比，2006年的疫情有更高的出血表现，成年男性人群受影响更大。在血小板计数降至每微升<20,000之前，未观察到血小板计数与不同出血表现之间的相关性。少数患者在血清转化前出现典型症状，突出了此类患者血液学而非免疫学特征受到的更大影响。非典型症状，如腹泻、月经过多和癫痫发作，往往是首发症状，而非登革热的典型临床特征。
