Sinha N, Gupta N, Jhamb R, Gulati S, Kulkarni Ajit V
Department of Medicine, Maulana Azad Medical College, New Delhi-110002.
J Commun Dis. 2008 Dec;40(4):243-8.
Dengue is a worldwide condition spread throughout the tropical and subtropical zones between 30 degrees north and 40 degrees south. It is endemic in South East Asia, the pacific, East and West Africa, the Caribbean and the Americas. Dengue outbreaks are occurring almost every three yearly in Delhi for the last 12 years. The latest outbreak was in the year 2006, which started late in August, peaked in the month of October and lasted till late November. We describe here the clinical, hematological and biochemical data of 70 patients of dengue fever diagnosed as per WHO criteria in Lok Nayak Hospital, New Delhi during this outbreak. Hematological parameters were estimated by automated counter and dengue serology was done by capture ELISA technique. The results displayed widespread effect of dengue fever on hematological and biochemical profile. Some of our patients also had atypical dengue manifestations. These results suggest that dengue fever is a major public health problem which can lead to significant morbidity and can even be fatal at times. All efforts should be made to prevent it.
登革热是一种全球性疾病,分布于北纬30度至南纬40度之间的热带和亚热带地区。在东南亚、太平洋地区、东非和西非、加勒比地区及美洲均为地方性流行。在过去12年里,德里几乎每三年就会爆发一次登革热疫情。最近一次疫情发生在2006年,8月底开始,10月达到高峰,一直持续到11月底。在此,我们描述了此次疫情期间,在新德里洛克纳亚克医院按照世界卫生组织标准诊断的70例登革热患者的临床、血液学和生化数据。血液学参数通过自动计数器进行评估,登革热血清学检测采用捕获ELISA技术。结果显示登革热对血液学和生化指标有广泛影响。我们的一些患者还表现出非典型的登革热症状。这些结果表明,登革热是一个主要的公共卫生问题,可导致严重发病,甚至有时会致命。应尽一切努力预防登革热。