Levité E M, Postoiuk N I
Anesteziol Reanimatol. 1991 Jan-Feb(1):55-7.
The improvement of combined anesthesia is associated with the improvement of its control. The latter is possible only with continuous administration of anesthetics. 130 procedures of combined anesthesia were performed in patients subject to abdominal and other types of operations. With this in view fentanyl and calipsol were continuously injected, using modified dosators, to patients pretreated with N2O and total curarization. It has been found that with continuous administration adequate analgesia with stable blood pressure can be achieved provided that 1/3-2/3 of the total fentanyl dose is used as a loading dose at the beginning of anesthesia. The maintenance dose does not change considerably blood anesthetic concentration. If required, changes in the concentrations were achieved by additional fentanyl administration, using a dosator for 25-50 mukg. The technique described has advantages over bolus drug injection and continuous drug infusion. The technique may be considered a controlled one.
复合麻醉的改善与其控制的改善相关。后者只有通过持续给予麻醉剂才有可能实现。对接受腹部及其他类型手术的患者进行了130例复合麻醉手术。考虑到这一点,使用改良的剂量器,对预先用氧化亚氮和完全箭毒化处理的患者持续注射芬太尼和卡利普索。已经发现,在持续给药的情况下,只要在麻醉开始时将芬太尼总剂量的1/3 - 2/3用作负荷剂量,就可以实现充分的镇痛且血压稳定。维持剂量不会使血液麻醉浓度发生显著变化。如果需要,通过使用25 - 50微克的剂量器额外给予芬太尼来实现浓度的变化。所描述的技术优于大剂量推注药物和持续药物输注。该技术可被认为是一种可控技术。