[创伤后嗅觉丧失：嗅觉事件相关电位与MRI评估]

[Posttraumatic anosmia: olfactory event related potentials and MRI evaluation].

作者信息

Liu Jian-Feng, You Hui, Ni Dao-Feng, Zhang Qiu-Hang, Yang Da-Zhang, Wang Na-Ya

机构信息

Department of Otorhinolaryngology, China-Japen Friendship Hospital, Beijing 100029, China.

出版信息

Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2008 Mar;43(3):198-201.

PMID:18630282

Abstract

OBJECTIVE

Using olfactory event related potentials (OERP) and magnetic resonance to evaluate olfactory function in patients with posttraumatic anosmia.

METHODS

Twenty four patients with posttraumatic anosmia were reviewed retrospectively. A thorough medical history, physical examination, nasal endoscopy, T&T olfactory testing, olfactory event-related potentials, brain computed tomography scan and magnetic resonance image of olfactory pathway were performed in all patients.

RESULTS

Subjective olfactory testing indicated 20 of 24 patients were birhinal anosmia, 2 with right nostril anosmia and left impairment, 2 with left anosmia and right normal. No OERP were obtained in 24 (20 were birhinal, 4 was monorhinal), except 4 cases with single nostril. Magnetic resonance imaging revealed the injures to the olfactory bulbs (100%), rectus gyrus (91.7%), orbital gyrus (67%), olfactory tracts (8%) and temporal lobes (8%).

CONCLUSIONS

OERP can objectively evaluate posttraumatic olfactory function, and magnetic resonance of olfactory pathway can precisely identify the location and extent of injures.

摘要

目的

运用嗅觉事件相关电位（OERP）和磁共振成像评估创伤后嗅觉障碍患者的嗅觉功能。

方法

对24例创伤后嗅觉障碍患者进行回顾性研究。所有患者均进行了详细的病史询问、体格检查、鼻内镜检查、T&T嗅觉测试、嗅觉事件相关电位检测、脑部计算机断层扫描以及嗅觉通路的磁共振成像检查。

结果

主观嗅觉测试显示，24例患者中20例为双侧嗅觉丧失，2例右侧鼻孔嗅觉丧失伴左侧嗅觉减退，2例左侧嗅觉丧失而右侧正常。24例患者（20例双侧、4例单侧）中除4例单侧鼻孔患者外均未引出OERP。磁共振成像显示嗅球损伤（100%）、直回损伤（91.7%）、眶回损伤（67%）、嗅束损伤（8%）以及颞叶损伤（8%）。