Tesar V
Klinika nefrologie 1. lékarské fakulty UK a VFN Praha.
Vnitr Lek. 2008 May;54(5):494-8.
Diabetic nephropathy is the most frequent cause of terminal renal failure in the Czech Republic today. Diabetic patients should be screened for diabetic kidney disease on an annual basis, starting 5 years after diabetes was diagnosed in type 1 diabetes patients and immediately after diagnosis in type 2 diabetes patients. The screening includes determining the albumin/creatinine ratio from a urine sample, and of serum creatinine, and the calculation ofglomerular filtration rate. In patients in whom microalbuminuria and/or proteinuria were found, measures should be taken to reduce cardiovascular risk and to slow down the progression of renal disease. In diabetic patients with abnormal urine test results detailed nephrology examination is necessary to exclude other renal diseases than diabetic nephropathy, especially chronic glomerulonephritis and ischaemic nephropathy.
糖尿病肾病是当今捷克共和国终末期肾衰竭最常见的病因。糖尿病患者应每年接受糖尿病肾病筛查,1型糖尿病患者在确诊糖尿病5年后开始,2型糖尿病患者在确诊后立即进行。筛查包括测定尿样中的白蛋白/肌酐比值、血清肌酐,并计算肾小球滤过率。对于发现有微量白蛋白尿和/或蛋白尿的患者,应采取措施降低心血管风险并减缓肾病进展。对于尿检结果异常的糖尿病患者,需要进行详细的肾脏病检查,以排除除糖尿病肾病以外的其他肾脏疾病,尤其是慢性肾小球肾炎和缺血性肾病。