Mathias Dietger, Gebhard Joachim, Wilhelm Lars, Schmidt-Gayk Heinrich, Mathias Ina
MVZ - Labor Dr. med. Kramer und Kollegen, Geesthacht, Germany.
Clin Lab. 2008;54(3-4):103-8.
The evaluation of the inter-laboratory tests over the 26 year period shows a clear improvement in the analysis quality of the test participants. This can be clearly seen in the increased recovery rates of the pathological quality control samples. Centers are put in the position to adjust their own quality control measures for their analysis to international standards, thereby decreasing the error rate in their analyses. The introduction of the tandem mass spectrometer for newborn screening is inevitably connected to even higher requirements in the quality of the measured values. Up to now, though, commercially or scientifically determined external quality controls do not exist. In November 2005, as a start, we tentatively expanded our (since 1982) existing inter-laboratory controls to include parameters determinable by mass spectrometry. A second external control will take place in May 2008 for acylcarnitines.
对26年间实验室间测试的评估表明，测试参与者的分析质量有了显著提高。这在病理质量控制样本回收率的提高中可以明显看出。各中心能够根据国际标准调整自身分析的质量控制措施，从而降低分析中的误差率。串联质谱仪用于新生儿筛查不可避免地对测量值质量提出了更高要求。然而，到目前为止，尚无商业或科学确定的外部质量控制。作为开始，我们于2005年11月初步将我们（自1982年以来）现有的实验室间控制扩展到包括可通过质谱法测定的参数。2008年5月将针对酰基肉碱进行第二次外部控制。
