Weinstock M A, Bogaars H A, Ashley M, Litle V, Bilodeau E, Kimmel S
Department of Medicine, Veterans Affairs Medical Center, Providence, RI 02908.
Arch Dermatol. 1991 Aug;127(8):1194-7.
To estimate the magnitude of nonmelanoma skin cancer mortality and describe its parameters, we reviewed the medical records of all deaths certified as due to this cause among Rhode Island residents from 1979 through 1987. After excluding acquired immunodeficiency syndrome-associated Kaposi's sarcoma, we confirmed that nonmelanoma skin cancer was the cause of death for 51 individuals, a quarter of the number of melanoma deaths reported. The age-adjusted nonmelanoma skin cancer mortality rate was 0.44/10(5) per year. Fifty-nine percent were due to squamous cell carcinoma, and 20% were due to basal cell carcinoma. Most appeared actinically induced. Among deaths from squamous cell carcinoma, the mean age was 73 years. At least 80% of the squamous cell carcinomas metastasized, and 47% arose on the ear. None appeared due to refusal of treatment. Among deaths from basal cell carcinoma, the mean age was 85 years, and refusal of surgical intervention was documented in 40%. Study of nonmelanoma skin cancer mortality provides for estimation of the magnitude of this problem, complements other studies of prognosis, and helps guide prevention, early detection, and treatment.
为了估算非黑素瘤皮肤癌的死亡率并描述其参数，我们查阅了1979年至1987年罗德岛居民中所有被证明死于该病因的死亡病历。在排除与获得性免疫缺陷综合征相关的卡波西肉瘤后，我们确认非黑素瘤皮肤癌是51人的死因，这一数字是报告的黑素瘤死亡人数的四分之一。年龄调整后的非黑素瘤皮肤癌死亡率为每年0.44/10万。59%的死亡归因于鳞状细胞癌，20%归因于基底细胞癌。大多数似乎是光化性诱导的。在鳞状细胞癌死亡病例中，平均年龄为73岁。至少80%的鳞状细胞癌发生了转移，47%发生在耳部。没有一例是因拒绝治疗而死亡。在基底细胞癌死亡病例中，平均年龄为85岁，40%有拒绝手术干预的记录。对非黑素瘤皮肤癌死亡率的研究有助于估算这一问题的严重程度，补充其他预后研究，并有助于指导预防、早期发现和治疗。
