Frentz G, Kulinsky B, Hjalgrim H, Osterlind A L
Rigshospitalet, Afdeling for rekonstruktionskirurgi, København.
Ugeskr Laeger. 1991 Feb 18;153(8):582-4.
Non-melanoma skin cancer (NMSC) differs from other forms of cancer by a high incidence combined with a very low lethality. In Denmark there is a well-established registration system of both the cause of death and the incidence of cancer. In 1984, 2,984 cases of NMSC were notified to the Cancer Register while, according to the Register of Causes of Death, 40 persons were registered as having died from NMSC. These 40 cases were investigated further by means of information from the case records and the general practitioners. In only 18 out of the 40 cases death was caused by NMSC, basal cell carcinoma with invasion into vital organs in three cases and metastasing spinocellular carcinoma in 15 cases. Over half of the fatal cases of spinocellular carcinoma were localized around the outer openings on the face, primarily (n = 4) around the external auditory meatus. In this review, the estimated lethality for basal cell carcinoma was 0.12% and for spinocellular carcinoma 4.3% the latter being high compared with other studies. Comparable population based studies are not available due to less effective registration systems.
非黑色素瘤皮肤癌（NMSC）与其他癌症形式不同，其发病率高但致死率极低。在丹麦，有一个完善的死亡原因和癌症发病率登记系统。1984年，癌症登记处收到2984例NMSC病例报告，而根据死亡原因登记处的数据，有40人登记死于NMSC。通过病例记录和全科医生提供的信息，对这40例病例进行了进一步调查。在这40例病例中，只有18例的死亡是由NMSC导致的，其中3例是基底细胞癌侵犯重要器官，15例是转移性棘细胞癌。超过一半的致命性棘细胞癌病例位于面部外部开口周围，主要（n = 4）是在外耳道周围。在本综述中，基底细胞癌的估计致死率为0.12%，棘细胞癌为4.3%，与其他研究相比，后者的致死率较高。由于登记系统效率较低，尚无基于人群的可比研究。
