Fraser R S
Department of Pathology, Montreal General Hospital, Quebec, Canada.
Arch Pathol Lab Med. 1991 Aug;115(8):751-61.
Transthoracic needle aspiration is a relatively innocuous procedure used extensively in the diagnosis of pulmonary disease. Although its sensitivity for malignancy is high, a negative (benign) diagnosis is obtained in 5% to 25% of all cases. Some of these aspirates represent the result of inadequate sampling of a malignant tumor; others, however, are derived from a truly benign process. This review briefly describes and illustrates the cytologic features of these latter aspirates in order to exemplify the wide range of benign diseases that can be identified or suspected by transthoracic needle aspiration. Familiarity with such features should help the interpreting pathologist to prevent needless respiration or thoracotomy in many patients.
经胸针吸活检是一种在肺部疾病诊断中广泛应用的相对无害的操作。尽管其对恶性肿瘤的敏感性较高，但在所有病例中，有5%至25%的病例会得出阴性（良性）诊断结果。其中一些吸出物是恶性肿瘤取样不足的结果；然而，其他的则源自真正的良性病变。本综述简要描述并举例说明了这些后者吸出物的细胞学特征，以例证经胸针吸活检可识别或怀疑的多种良性疾病。熟悉这些特征应有助于解读病理的医生避免许多患者进行不必要的呼吸检查或开胸手术。
