Jiang Jianping, Zheng Xiangyi, Qin Jie, Zheng Mingzhi, Mao Qiqi, Zhang Zhigen, Cai Songliang, Xie Liping
Department of Urology, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang 310003, China.
Int Urol Nephrol. 2009;41(1):23-7. doi: 10.1007/s11255-008-9429-5. Epub 2008 Jul 17.
To compare the health-related quality of life (HRQOL) in contemporaneous groups of patients undergoing hand-assisted laparoscopic radical nephrectomy (HALRN) or open radical nephrectomy (ORN) for renal cell carcinoma (RCC).
The clinical data of 20 cases receiving hand-assisted laparoscopic radical nephrectomy (the HALRN group) and 51 cases receiving open radical nephrectomy (the ORN group) were analyzed retrospectively and health questionnaires were mailed to these patients at 1 year postoperatively. The two groups were compared in terms of general surgery-related information, tumor characteristics, days to return to work or routine daily activities, and health-related quality-of-life scales.
Patients in the HALRN group had significantly less mean incision length (6.25 versus 17.8 cm), faster return to work or routine daily activities (5.3 versus 8.6 weeks), and earlier out-of-bed activity (4.76 versus 6.59 days) compared with those in the ORN group (P < 0.05). There were no significant differences in HRQOL scales at 1 year between the both groups (P > 0.05).
The results showed that hand-assisted laparoscopic surgery is a minimally invasive surgical technique for RCC offering earlier recovery and similar long-term HRQOL compared with open surgery.
比较同期接受手辅助腹腔镜根治性肾切除术（HALRN）或开放性根治性肾切除术（ORN）治疗肾细胞癌（RCC）患者的健康相关生活质量（HRQOL）。
回顾性分析20例行手辅助腹腔镜根治性肾切除术患者（HALRN组）和51例行开放性根治性肾切除术患者（ORN组）的临床资料，并在术后1年向这些患者邮寄健康调查问卷。比较两组患者的一般外科相关信息、肿瘤特征、恢复工作或日常活动的天数以及健康相关生活质量量表。
与ORN组相比，HALRN组患者的平均切口长度明显更短（6.25 cm对17.8 cm），恢复工作或日常活动更快（5.3周对8.6周），下床活动更早（4.76天对6.59天）（P<0.05）。两组在术后1年的HRQOL量表方面无显著差异（P>0.05）。
结果表明，手辅助腹腔镜手术是一种治疗RCC的微创手术技术，与开放手术相比，恢复更快，长期HRQOL相似。
