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[以提示疱疹性脑炎的初始症状起病的原发性中枢神经系统淋巴瘤]

[Primary central nervous system lymphoma with initial symptoms suggesting herpes encephalitis].

作者信息

Kułakowska Alina, Pogorzelski Robert, Drozdowski Wiesław

机构信息

Akademia Medyczna w Białymstoku, Klinika Neurologii.

出版信息

Pol Merkur Lekarski. 2008 Jan;24(139):30-3.

PMID:18634249
Abstract

Primary central nervous system lymphoma (PCNSL) is rare neoplasm, affecting both immunocompetent and immunodeficient patients. It is usually seen as intracranial tumor, but it can often involve cerebrospinal meninges, eyeballs and spinal cord. Although PCNSL is sensitive both to radiotheraphy and chemotheraphy, it's recurrences are very frequent. Mean survival time does not exceed several months. We described a case of 43 year old patient with diagnosed PCNSL and discussed clinical signs, diagnostics and treatment of the neoplasm. In our case report we emphasized transient remission after treatment with corticosteroids, which delayed a correct diagnosis and worsened final prognosis.

摘要

原发性中枢神经系统淋巴瘤(PCNSL)是一种罕见的肿瘤,可发生于免疫功能正常和免疫功能低下的患者。它通常表现为颅内肿瘤,但也常累及脑脊膜、眼球和脊髓。尽管PCNSL对放疗和化疗均敏感,但其复发非常频繁。平均生存时间不超过数月。我们描述了一例43岁确诊为PCNSL的患者,并讨论了该肿瘤的临床症状、诊断和治疗。在我们的病例报告中,我们强调了使用糖皮质激素治疗后的短暂缓解,这延迟了正确诊断并恶化了最终预后。

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