Pradhan H K, Gurbuxani J P, Cliquet F, Pattnaik B, Patil S S, Regnault A, Begouen H, Guiot A L, Sood R, Mahl P, Singh R, Picard E, Aubert M F A, Barrat J, Meslin F X
HSADL-High SecurityAnimal Disease Laboratory, Indian Veterinary Research Institute, Anand Nagar, Madhya Pradesh, India.
Dev Biol (Basel). 2008;131:157-66.
In India, about 20,000 people die of rabies every year. The dog is the main reservoir and transmitter of the disease. A pilot rabies control programme was launched in five Indian federal states in February, 2007. This initiative is led by the Animal Welfare Board of India (AWBI) federating many animal welfare organizations and the Ministry of Agriculture. It aims at creating a "Rabies Free India." The programme combines parenteral vaccination of accessible owned and stray dogs, spaying/neutering followed by parenteral vaccination and oral vaccination of inaccessible dogs. The freeze-dried vaccine SAG2, including the bait casing, was registered in India following successful evaluation of vaccine-bait safety and efficacy (by survival after virulent challenge) in captive Indian stray dogs in the Bhopal High Security Animal Disease Laboratory. Furthermore, bait acceptance was tested under both experimental and field conditions.
在印度，每年约有2万人死于狂犬病。狗是这种疾病的主要宿主和传播者。2007年2月，印度五个联邦邦启动了一项狂犬病控制试点项目。该倡议由印度动物福利委员会（AWBI）牵头，联合了许多动物福利组织和农业部。其目标是打造一个“无狂犬病印度”。该项目结合了对可接触到的家养犬和流浪犬进行肌肉注射疫苗、绝育后再进行肌肉注射疫苗以及对难以接触到的犬只进行口服疫苗。冻干疫苗SAG2（包括诱饵外壳）在博帕尔高安全动物疾病实验室对圈养的印度流浪犬成功进行疫苗-诱饵安全性和有效性评估（通过强毒攻击后的存活情况）后，在印度注册。此外，还在实验和实地条件下对诱饵的接受情况进行了测试。
