Vujanić G M, Dojĉinov D
Department of Paediatric Pathology, Mother and Child Health Institute, Belgrade, Yugoslavia.
Pediatr Hematol Oncol. 1991 Apr-Jun;8(2):121-9. doi: 10.3109/08880019109033439.
Two children with inflammatory pseudotumor (IPT) of the lung are reported. Symptomless "cystic" lesions were present on routine chest x ray. Morphological study of these peculiar lesions included light microscopic, immunohistochemical, and ultrastructural analysis. Histologic appearance of the lesion varied from the features of granulation tissue on the periphery to bundles of spindle-shaped cells in the central area. Immunohistochemical findings had no diagnostic value but were helpful in excluding other tumors. Ultrastructural analysis confirmed the mixed cellular composition and benign nature of the lesion. Etiopathogenesis of this process is unknown. IPT can be differentiated from similar lesions and must not be mistaken for malignant tumor. Proper treatment by complete surgical removal of the lesion usually cures the patient.
本文报道了两名患有肺部炎性假瘤（IPT）的儿童。常规胸部X光检查发现无症状的“囊性”病变。对这些特殊病变的形态学研究包括光镜、免疫组织化学和超微结构分析。病变的组织学表现从周边的肉芽组织特征到中央区域的梭形细胞束各不相同。免疫组织化学结果虽无诊断价值，但有助于排除其他肿瘤。超微结构分析证实了病变的混合细胞组成和良性性质。该过程的病因发病机制尚不清楚。IPT可与类似病变相鉴别，绝不能误诊为恶性肿瘤。通过完整手术切除病变进行恰当治疗通常可治愈患者。
