Soar K, Parrott A, Turner J
Department of Psychology, University of East London, London, UK.
J Psychopharmacol. 2009 Sep;23(7):745-58. doi: 10.1177/0269881108092594. Epub 2008 Jul 17.
Ecstasy [3,4-methylenedioxymethamphetamine (MDMA)] use has been associated with a number of psychopathological problems. However, research suggests that reported symptoms might be associated more with heavy polydrug use in general rather than ecstasy per se. The current study aimed to determine the role of other drug use in reports of long-term effects by some ecstasy-polydrug users. Problematic ecstasy users (n = 53), reporting problems which they attributed to ecstasy use, were compared with non-problematic ecstasy users (n = 62), polydrug (n = 62) and alcohol/nicotine using controls (n = 111). Drug use was recorded, and positive and negative life changes were assessed along with which previous drug use, if any, they attributed these changes too. Both ecstasy groups reported higher drug use compared with polydrug controls. Polydrug and ecstasy users more often reported life changes compared with non-drug users, and ecstasy users appeared to experience more life changes than polydrug users, with problematic ecstasy users experiencing most alterations. Ecstasy users reported changes more to a combination of drugs than to one specific drug, suggesting that polydrug use in these groups has an impact on their life experiences. These findings emphasise that research into the psychological effects of ecstasy should not underestimate the role of other polydrug use.
摇头丸[3,4-亚甲基二氧甲基苯丙胺（MDMA）]的使用与许多精神病理学问题有关。然而，研究表明，所报告的症状可能更多地与总体上大量使用多种药物有关，而非摇头丸本身。当前的研究旨在确定在一些摇头丸-多种药物使用者报告的长期影响中其他药物使用所起的作用。将有问题的摇头丸使用者（n = 53，报告他们归因于摇头丸使用的问题）与无问题的摇头丸使用者（n = 62）、多种药物使用者（n = 62）以及使用酒精/尼古丁的对照组（n = 111）进行比较。记录药物使用情况，并评估积极和消极的生活变化，以及他们将这些变化归因于之前的何种药物使用（如果有的话）。与多种药物使用对照组相比，两个摇头丸组报告的药物使用量更高。与非药物使用者相比，多种药物使用者和摇头丸使用者更常报告生活变化，并且摇头丸使用者似乎比多种药物使用者经历更多的生活变化，有问题的摇头丸使用者经历的变化最多。摇头丸使用者报告的变化更多是多种药物共同作用的结果，而非某一种特定药物，这表明这些群体中的多种药物使用对他们的生活经历有影响。这些发现强调，对摇头丸心理影响的研究不应低估其他多种药物使用所起的作用。
