Parrott A C, Buchanan T, Scholey A B, Heffernan T, Ling J, Rodgers J
Recreational Drugs Research Group, School of Psychology, University of East London, London E15 4LZ, UK.
Hum Psychopharmacol. 2002 Aug;17(6):309-12. doi: 10.1002/hup.415.
The recreational use of MDMA/Ecstasy (3,4-methylenedioxymethamphetamine) is associated with many psychobiological problems, but there is a paucity of data on how these relate to the level of past use.
to assess the incidence of Ecstasy-attributed problems as reported by novice, moderate and heavy users.
763 unpaid volunteers took part in a WWW study of recreational drug use. This report is based on the 282 Ecstasy users from that sample, who comprised 109 novice users (1-9 occasions), 136 moderate users (10-99 occasions), and 36 heavy users (+100 occasions). Yes/no responses were automatically recorded to a series of questions covering psychobiological problems experienced when drug-free, which were attributed by the respondents to their Ecstasy use.
Depression, memory problems, anxiety, mood fluctuation, poor concentration, infections, tremors/twitches and weight loss, were all significantly associated with the extent of Ecstasy use. Thus memory problems attributed to Ecstasy were reported by 19% of novice users, 52% of heavy users and 73% of heavy users (chi-square 42.74, df=2, p<0.001); many of the other variables showed similar trends.
The incidence of problems attributed to Ecstasy use, is directly related to the number of occasions it has been used.
摇头丸/迷幻药(3,4-亚甲基二氧甲基苯丙胺)的娱乐性使用与许多心理生物学问题相关,但关于这些问题如何与过去的使用水平相关的数据却很少。
评估新手、中度使用者和重度使用者报告的由摇头丸引起的问题的发生率。
763名无报酬志愿者参与了一项关于娱乐性药物使用的网络研究。本报告基于该样本中的282名摇头丸使用者,其中包括109名新手使用者(1 - 9次)、136名中度使用者(10 - 99次)和36名重度使用者(+100次)。针对一系列关于在未使用药物时所经历的心理生物学问题的问题,自动记录“是/否”回答,这些问题由受访者归因于他们使用摇头丸所致。
抑郁、记忆问题、焦虑、情绪波动、注意力不集中、感染、震颤/抽搐和体重减轻,均与摇头丸的使用程度显著相关。因此,19%的新手使用者、52%的中度使用者和73%的重度使用者报告称存在归因于摇头丸的记忆问题(卡方检验42.74,自由度 = 2,p < 0.001);许多其他变量也呈现出类似趋势。
归因于摇头丸使用的问题发生率与使用次数直接相关。