Luck Tobias, Luppa Melanie, Weber Stephan, Matschinger Herbert, Glaesmer Heide, Konig Hans-Helmut, Angermeyer Matthias C, Riedel-Heller Steffi G
Public Mental Health Research Unit, Department of Psychiatry, University of Leipzig, Leipzig, Germany.
Neuroepidemiology. 2008;31(2):100-8. doi: 10.1159/000146251. Epub 2008 Jul 21.
Information on the time until institutionalization and its predictors in demented subjects has so far been based on studies with selected samples or prevalent dementia cases. Thus, the aim of the study is to analyze the time until institutionalization and associated patient-related factors in incident dementia cases.
Data were derived from the Leipzig Longitudinal Study of the Aged (LEILA 75+), a population-based study of individuals aged 75 years and older. Kaplan-Meier survival analysis was used to determine the time until institutionalization. Factors associated with time until institutionalization were analyzed using Cox proportional hazards models.
One hundred and nine subjects with incident dementia who resided in a private home setting at the time of the dementia diagnosis were identified. Fifty-two (47.7%) of these subjects had become residents of a nursing home by the end of the study. The median time until institutionalization was 1,005 days (95% CI = 808-1,202). Being widowed/divorced (compared to being married) was associated with a significantly shorter time until institutionalization (univariate model: HR = 4.50, 95% CI = 1.09-18.57).
Being without a spouse seems to be an important factor for a shorter time until institutionalization in incident dementia cases. Tailored interventions for these subjects at risk are required.
到目前为止,关于痴呆患者进入机构照料的时间及其预测因素的信息是基于对选定样本或现患痴呆病例的研究。因此,本研究的目的是分析新发痴呆病例进入机构照料的时间及相关的患者因素。
数据来源于莱比锡老年纵向研究(LEILA 75+),这是一项针对75岁及以上人群的基于人群的研究。采用Kaplan-Meier生存分析来确定进入机构照料的时间。使用Cox比例风险模型分析与进入机构照料时间相关的因素。
确定了109例新发痴呆患者,他们在痴呆诊断时居住在私人住宅中。到研究结束时,这些患者中有52例(47.7%)成为养老院居民。进入机构照料的中位时间为1005天(95%CI = 808-1202)。丧偶/离婚(与已婚相比)与进入机构照料的时间显著缩短相关(单变量模型:HR = 4.50,95%CI = 1.09-18.57)。
在新发痴呆病例中,没有配偶似乎是进入机构照料时间较短的一个重要因素。需要针对这些高危患者进行量身定制的干预措施。