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[常用药物的治疗和中毒血浆浓度及消除半衰期]

[Therapeutic and toxic plasma concentrations and elimination half-lives of commonly used drugs].

作者信息

Schulz M, Wischhusen F, Schmoldt A

机构信息

Institut für Rechtsmedizin, Universität Hamburg.

出版信息

Anasthesiol Intensivmed Notfallmed Schmerzther. 1991 Feb;26(1):37-43. doi: 10.1055/s-2007-1000534.

DOI:10.1055/s-2007-1000534
PMID:1863682
Abstract

For 253 frequently used drugs therapeutic and, if data were available, toxic, and fatal plasma concentrations as well as elimination half-lives were compiled in a table. To assess the significance of drug levels for the therapeutic monitoring of patients, it is essential that a collection of data is readily available. In addition, this list can assist the diagnostic assessment in case of intoxications.

摘要

针对253种常用药物,将其治疗性血浆浓度(若有数据,还包括毒性和致死性血浆浓度)以及消除半衰期汇编成表格。为评估药物水平对患者治疗监测的重要性,必须随时可得一系列数据。此外,该列表在中毒情况下有助于诊断评估。

相似文献

1
[Therapeutic and toxic plasma concentrations and elimination half-lives of commonly used drugs].[常用药物的治疗和中毒血浆浓度及消除半衰期]
Anasthesiol Intensivmed Notfallmed Schmerzther. 1991 Feb;26(1):37-43. doi: 10.1055/s-2007-1000534.
2
Therapeutic and toxic blood concentrations of more than 800 drugs and other xenobiotics.800多种药物及其他外源性物质的治疗性和中毒性血药浓度。
Pharmazie. 2003 Jul;58(7):447-74.
3
Therapeutic and toxic blood concentrations of more than 500 drugs.500多种药物的治疗血药浓度和中毒血药浓度。
Pharmazie. 1997 Dec;52(12):895-911.
4
Indicative therapeutic and toxic drug concentrations in plasma: a tabulation.血浆中具有指示性的治疗和中毒药物浓度:一览表。
Int J Clin Pharmacol Ther. 1994 Feb;32(2):71-81.
5
[A compilation of therapeutic and toxic plasma drug concentrations].[治疗性和毒性血浆药物浓度汇编]
Anaesthesist. 1994 Dec;43(12):835-44. doi: 10.1007/s001010050126.
6
[Individualization of drug dosage by therapeutic monitoring in plasma and the application of pharmacokinetic principles].[通过血浆治疗监测实现药物剂量个体化及药代动力学原理的应用]
J Clin Chem Clin Biochem. 1983 Nov;21(11):649-58.
7
[Therapeutic monitoring of drugs as a real progress in drug therapy].[药物治疗监测——药物治疗的一项真正进展]
Wiad Lek. 1992 Jan;45(1-2):73-9.
8
[Monitoring of therapy using drug concentration levels: Why? When? How?].
Ther Umsch. 1990 Aug;47(8):635-9.
9
Pharmacokinetics in patients with renal failure.肾衰竭患者的药代动力学。
Clin Nephrol. 1984 Jan;21(1):39-46.
10
Primer on clinical pharmacokinetics.临床药代动力学基础
Am J Hosp Pharm. 1983 Oct;40(10):1637-41.

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