Crown J, Lipzstein R, Cohen S, Goldsmith M, Wisch N, Paciucci P A, Silverman L, Weiner M, Jaffrey I, Norton L
Department of Neoplastic Diseases, Mount Sinai Medical Center, New York, New York 10029.
Cancer Invest. 1991;9(2):129-32. doi: 10.3109/07357909109044222.
Out of 16 cases of Merkel cell cancer identified in the records of the Mt. Sinai Medical Center or affiliates, 11 patients developed systemic metastases. Literature review confirms the substantial possibility of dissemination. Both in our series and in the literature, cytotoxic chemotherapy produced a high rate of usually short-lived response, although one of our patients with disseminated metastases achieved complete remission for two years.
在西奈山医疗中心及其附属医院的记录中确诊的16例默克尔细胞癌病例中，有11例患者发生了全身转移。文献综述证实了转移的极大可能性。在我们的系列病例以及文献中，细胞毒性化疗通常产生较高比例的短期缓解，尽管我们的一名发生广泛转移的患者实现了两年的完全缓解。
