Müller U, Mosbech H, Blaauw P, Dreborg S, Malling H J, Przybilla B, Urbanek R, Pastorello E, Blanca M, Bousquet J
Medizinische Klinik, Zieglerspital, Bern, Switzerland.
Clin Exp Allergy. 1991 May;21(3):281-8. doi: 10.1111/j.1365-2222.1991.tb01659.x.
Allergic reactions to Hymenoptera stings are frequently observed all over Europe. Rarely they may induce long-standing morbidity or even be fatal. Several investigations have shown that the emergency treatment given to these patients is often inadequate. Cutaneous symptoms respond well to antihistamines and also to adrenaline. Adrenaline is the mainstay for outside hospital treatment of more severe reactions involving the respiratory tract (bronchial asthma, laryngeal oedema) and the cardiovascular system (anaphylactic shock). Inhaled adrenaline is especially useful in respiratory symptoms, while parenteral application of adrenaline is prefered for shock treatment. All patients with severe respiratory or cardiovascular reactions must be hospitalized, treated under intensive care conditions and observed for at least 24 hr. Emergency medications including adrenaline for inhalation or for self-injection must be given to all patients with a history of systemic allergic reactions to hymenoptera stings. These patients must also get instructions for safety measures to avoid further stings. They should be referred to an allergist in order to evaluate the indication for venom immunotherapy.
在欧洲各地,经常观察到对膜翅目昆虫叮咬的过敏反应。这些反应很少会导致长期发病,甚至可能是致命的。多项调查表明,给予这些患者的紧急治疗往往不足。皮肤症状对抗组胺药以及肾上腺素反应良好。肾上腺素是院外治疗涉及呼吸道(支气管哮喘、喉水肿)和心血管系统(过敏性休克)的更严重反应的主要药物。吸入性肾上腺素对呼吸道症状特别有用,而注射用肾上腺素则更适合用于休克治疗。所有有严重呼吸或心血管反应的患者都必须住院,在重症监护条件下接受治疗,并观察至少24小时。必须为所有有膜翅目昆虫叮咬全身性过敏反应病史的患者提供包括吸入用或自行注射用肾上腺素在内的急救药物。这些患者还必须得到关于避免再次被叮咬的安全措施的指导。他们应被转诊至过敏症专科医生处,以评估毒液免疫治疗的适应症。