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定量分流显像在评估肺动静脉畸形患者治疗性手术中的应用

Quantitative shunt imaging in the evaluation of therapeutic surgery in a patient with pulmonary arteriovenous malformation.

作者信息

Ones Tunc, Dede Fuat, Erdim Refik, Erdil Tanju Yusuf, Inanir Sabahat, Yuksel Mustafa, Turoglu Halil Turgut

机构信息

Department of Nuclear Medicine, Marmara University School of Medicine, Istanbul, Turkey.

出版信息

Ann Thorac Surg. 2008 Aug;86(2):649-51. doi: 10.1016/j.athoracsur.2008.02.020.

DOI:10.1016/j.athoracsur.2008.02.020
PMID:18640353
Abstract

A case of pulmonary arteriovenous malformation (PAVM) in a 32-year-old woman who underwent successful left upper lobectomy is presented. A whole-body technetium-99m-labeled macro-aggregated albumin scan was used to demonstrate intrapulmonary right-to-left shunt, and shunt fraction was calculated as 39%. The patient underwent a follow-up scan after the operation; shunt fraction was calculated to be within normal limits (5%). The whole-body technetium-99m-labeled macro-aggregated albumin scan seems to be a simple and noninvasive test in the demonstration and quantitation of the degree of the right-to-left shunt in pulmonary arteriovenous malformation. The whole-body technetium-99m-labeled macro-aggregated albumin scan may also be useful for evaluation of the hemodynamic changes after surgical treatment and follow-up of the patients with pulmonary arteriovenous malformation.

摘要

本文介绍了一例32岁女性肺动静脉畸形(PAVM)患者,该患者接受左上叶切除术并获成功。采用全身锝-99m标记的大聚合白蛋白扫描来显示肺内右向左分流,计算得出分流分数为39%。患者术后接受了随访扫描;计算得出分流分数在正常范围内(5%)。全身锝-99m标记的大聚合白蛋白扫描似乎是一种简单且无创的检查方法,可用于显示和定量肺动静脉畸形中的右向左分流程度。全身锝-99m标记的大聚合白蛋白扫描对于评估手术治疗后血流动力学变化以及肺动静脉畸形患者的随访也可能有用。

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1
Quantitative shunt imaging in the evaluation of therapeutic surgery in a patient with pulmonary arteriovenous malformation.定量分流显像在评估肺动静脉畸形患者治疗性手术中的应用
Ann Thorac Surg. 2008 Aug;86(2):649-51. doi: 10.1016/j.athoracsur.2008.02.020.
2
[The scintigraphic 99mTc-MAA imaging quantification of the right-to-left shunt in a patients with multiple pulmonary arteriovenous malformation and familial teleangiectasis].[99mTc-MAA闪烁显像对多发性肺动静脉畸形和家族性毛细血管扩张症患者右向左分流的定量分析]
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Pulmonary arteriovenous malformations: effect of embolization on right-to-left shunt, hypoxemia, and exercise tolerance in 66 patients.肺动静脉畸形:66例患者栓塞治疗对右向左分流、低氧血症及运动耐量的影响
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Scintigraphic evaluation of small pulmonary right-to-left shunt and therapeutic effect in pulmonary arteriovenous malformation.肺动静脉畸形中小肺内右向左分流的闪烁显像评估及治疗效果
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Tc-99m MAA total-body imaging to detect intrapulmonary right-to-left shunts and to evaluate the therapeutic effect in pulmonary arteriovenous shunts.锝-99m 大颗粒聚合白蛋白全身显像用于检测肺内右向左分流及评估肺动静脉分流的治疗效果。
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引用本文的文献

1
Pulmonary arteries: imaging of pulmonary embolism and beyond.肺动脉:肺栓塞及其他疾病的影像学检查
Cardiovasc Diagn Ther. 2019 Aug;9(Suppl 1):S37-S58. doi: 10.21037/cdt.2018.08.05.
2
Review of diagnostic uses of shunt fraction quantification with technetium-99m macroaggregated albumin perfusion scan as illustrated by a case of Osler-Weber-Rendu syndrome.以奥斯勒-韦伯-伦杜综合征病例为例,探讨锝-99m 大颗粒聚合白蛋白灌注扫描定量分流分数在诊断中的应用。
Ann Thorac Med. 2016 Apr-Jun;11(2):155-60. doi: 10.4103/1817-1737.180020.