Okumura Akihisa, Hayakawa Fumio, Kato Toru, Suzuki Motomasa, Tsuji Takeshi, Fukumoto Yukiko, Nakata Tomohiko, Watanabe Kazuyoshi, Morishima Tsuneo
Department of Pediatrics, Juntendo University School of Medicine, 2-1-1 Hongo, Bunkyo-ku, Tokyo 113-8421, Japan.
Brain Dev. 2009 Feb;31(2):158-62. doi: 10.1016/j.braindev.2008.06.002. Epub 2008 Jul 21.
We retrospectively reviewed electroencephalography and magnetic resonance imaging findings for 21 children exhibiting delirious behavior during febrile illness. Among these, five patients had transient callosal lesions with or without white matter lesions on diffusion-weighted images. We compared the clinical characteristics, duration, and components of delirious behavior, the duration and severity of reduced consciousness, and EEG findings among patients with or without callosal lesions. No significant differences were detected in these items according to the presence or absence of callosal lesions. Adding insight into the pathogenesis of this condition, our study revealed that callosal lesions are not uncommon in patients exhibiting delirious behavior during febrile illness.
我们回顾性分析了21例在发热性疾病期间出现谵妄行为的儿童的脑电图和磁共振成像结果。其中，5例患者在扩散加权图像上有或无白质病变的胼胝体短暂性病变。我们比较了有或无胼胝体病变患者的临床特征、谵妄行为的持续时间和组成部分、意识减退的持续时间和严重程度以及脑电图结果。根据胼胝体病变的有无，在这些项目中未检测到显著差异。我们的研究进一步深入了解了这种疾病的发病机制，发现胼胝体病变在发热性疾病期间出现谵妄行为的患者中并不少见。
