Suppr超能文献

[术前淋巴闪烁显像对乳腺癌患者前哨淋巴结识别的意义]

[Interest of preoperative lymphoscintigraphy on sentinel lymph node identification in patients with breast cancer].

作者信息

Tulpin L, Morel O, Akerman G, Malartic C, Desfeux P, Barranger E

机构信息

Service de gynécologie-obstétrique, hôpital Lariboisière, AP-HP, 2 rue Ambroise-Paré, Paris, France.

出版信息

Gynecol Obstet Fertil. 2008 Jul-Aug;36(7-8):808-14. doi: 10.1016/j.gyobfe.2008.06.006. Epub 2008 Jul 21.

Abstract

Sentinel lymph node biopsy is nowadays an accepted method of staging breast cancer patients. In case of an injection of radioactive colloid, preoperative lymphoscintigraphy is recommended to establish a lymphatic mapping and to predict the number of sentinel lymph nodes identified during surgery. Preoperative lymphoscintigraphy does not decrease the false-negative rate. However, positive preoperative lymphoscintigraphy significantly improves the identification rate of intraoperative sentinel nodes comparing with negative preoperative lymphoscintigraphy. Detecting extra-axillary sentinel lymph nodes, because of its minimal therapeutic consequences, does not appear to be an indication for preoperative lymphoscintigraphy. Given logistics and cost required, preoperative lymphoscintigraphy should be only performed for patients with a high risk of intraoperative failed localization. In case of negative preoperative lymphoscintigraphy, sentinel lymph node biopsy must be tried because sentinel nodes are still identified in the majority of these patients. Another possibility, with important cost and logistic, should consist in performing a later lymphoscintigraphy on the day after radioactive injection to ameliorate sentinel lymph nodes identification.

摘要

前哨淋巴结活检如今是乳腺癌患者分期的一种公认方法。在注射放射性胶体的情况下,建议进行术前淋巴闪烁显像以建立淋巴图谱并预测手术中识别出的前哨淋巴结数量。术前淋巴闪烁显像不会降低假阴性率。然而,与术前淋巴闪烁显像阴性相比,术前淋巴闪烁显像阳性可显著提高术中前哨淋巴结的识别率。由于其治疗后果极小,检测腋外前哨淋巴结似乎并非术前淋巴闪烁显像的指征。考虑到所需的后勤保障和成本,术前淋巴闪烁显像仅应在术中定位失败风险高的患者中进行。如果术前淋巴闪烁显像为阴性,必须尝试进行前哨淋巴结活检,因为这些患者中的大多数仍可识别出前哨淋巴结。另一种可能性成本高昂且后勤保障复杂,即在放射性注射后第二天进行后期淋巴闪烁显像以改善前哨淋巴结的识别。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验