乳腺癌前哨淋巴结：手术中检查所带来的问题。当前文献及管理综述
The Sentinel Lymph Node in Breast Cancer: Problems Posed by Examination During Surgery. A Review of Current Literature and Management.
作者信息
Bouquet de Jolinière Jean, Major A, Khomsi F, Ben Ali N, Guillou L, Feki A
机构信息
Department of Gynecology Obstetrics, Cantonal Hospital, HFR, Fribourg, Switzerland.
Argotlab and Synlab Laboratories, Department of Pathology, Lausanne, Switzerland.
出版信息
Front Surg. 2018 Nov 14;5:56. doi: 10.3389/fsurg.2018.00056. eCollection 2018.
The presence of tumor cells can be identified in the lymph node when metastasis has occurred from the primary cancer site into the lymph node (1) If the sentinel lymph node ganglion is negative for the presence of tumor cells at the time of histological examination, the other lymph nodes are also negative in 99% of cases. If no tumor cells are identified in the sentinel lymph node ganglion by histological examination, the other lymph nodes are also negative for the presence of tumor cells in 99% of cases. The sentinel lymph node advantageously replaces axillary dissection as a staging method in breast cancer T1 and T2 (2). Approximately 40% of breast cancers metastasize to axillary lymph nodes and metastatic extension depends on disease stage. Sentinel lymph nodes are affected in the following stages: T1a (4.3%), T1b (19.5%), T1c (23.8%), T2 (48.9%), T3 (66.7%).
当原发癌部位发生转移至淋巴结时，可在淋巴结中识别出肿瘤细胞。（1）如果在组织学检查时前哨淋巴结神经节未发现肿瘤细胞，则在99%的病例中其他淋巴结也为阴性。如果通过组织学检查在前哨淋巴结神经节中未识别出肿瘤细胞，则在99%的病例中其他淋巴结也不存在肿瘤细胞。前哨淋巴结作为乳腺癌T1和T2分期方法，有利地取代了腋窝清扫术。（2）大约40%的乳腺癌会转移至腋窝淋巴结，转移范围取决于疾病分期。前哨淋巴结在以下分期中会受到影响：T1a（4.3%）、T1b（19.5%）、T1c（23.8%）、T2（48.9%）、T3（66.7%）。
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