Silva Luciano Bruno de Carvalho, Mourão Lucia Figueiredo, Silva Ariovaldo Armando, Lima Núbia Maria Freire Vieira, Almeida Sara Regina, Franca Marcondes C, Nucci Anamarli, Amaya-Farfán Jaime
Food and Nutrition Department, Center for Food Security Studies, School of Food Engineering, University of Campinas, Campinas, SP, Brazil.
Arq Neuropsiquiatr. 2008 Jun;66(2B):354-9. doi: 10.1590/s0004-282x2008000300014.
To establish correlations between nutritional, functional and respiratory indices of patients with amyotrophic lateral sclerosis (ALS).
Twenty patients (13 appendicular-GA and 7 bulbar-GB) were included in the multidisciplinary study at the Neurological Clinic Ambulatory of the University of Campinas Hospital.
Among the GA type significant correlation was observed between maximal inspiratory (MIP) and expiratory (MEP) pressure (r=-0.76), MEP and pulse oxymetry (r=0.58), MIP and percent weight loss (%WL; r=0.59), and between MIP, total and subscale respiratory scores (ALSFRS-R) with %WL. With regard to the GB, correlation was found between MEP and body mass index (BMI) (r=0.97). In both GA and GB correlations were noticed between the BMI and the variables mass (kg), fat (%), arm and wrist circumference (cm), and tricipital, subscapular and supra-iliac skinfolds (mm), as well as the arm muscle circumference (cm) and fatty arm muscular area (mm2).
It is suggested that the application of simple anthropometric measurements could be useful in routine monitoring of patients with ALS.
建立肌萎缩侧索硬化症（ALS）患者营养、功能和呼吸指标之间的相关性。
20例患者（13例肢体型GA和7例延髓型GB）纳入坎皮纳斯大学医院神经科门诊的多学科研究。
在GA型患者中，最大吸气压力（MIP）和最大呼气压力（MEP）之间观察到显著相关性（r = -0.76），MEP与脉搏血氧饱和度之间（r = 0.58），MIP与体重减轻百分比（%WL；r = 0.59）之间，以及MIP、总呼吸评分和亚量表呼吸评分（ALSFRS-R）与%WL之间存在显著相关性。对于GB型患者，MEP与体重指数（BMI）之间存在相关性（r = 0.97）。在GA型和GB型患者中，均发现BMI与体重（kg）、脂肪（%）、手臂和手腕周长（cm）、三头肌、肩胛下和髂上皮肤褶皱（mm）以及手臂肌肉周长（cm）和手臂脂肪肌肉面积（mm²）等变量之间存在相关性。
建议应用简单的人体测量方法有助于ALS患者的常规监测。
