Ibarz Borja, Cao Hongjun, Sanjuán Miguel A F
Nonlinear Dynamics and Chaos Group, Departamento de Física, Universidad Rey Juan Carlos, Tulipán s/n, 28933 Móstoles, Madrid, Spain.
Phys Rev E Stat Nonlin Soft Matter Phys. 2008 May;77(5 Pt 1):051918. doi: 10.1103/PhysRevE.77.051918. Epub 2008 May 30.
A system consisting of two map-based neurons coupled through reciprocal excitatory or inhibitory chemical synapses is discussed. After a brief explanation of the basic mechanism behind generation and synchronization of bursts, parameter space is explored to determine less obvious but biologically meaningful regimes and effects. Among them, we show how excitatory synapses without any delays may induce antiphase synchronization; that a synapse may change its character from excitatory to inhibitory and vice versa by changing its conductance, without any change in reversal potential; and that small variations in the synaptic threshold may result in drastic changes in the synchronization of spikes within bursts. Finally we show how the synchronization effects found in the two-neuron system carry over to larger networks.
讨论了一个由两个通过相互兴奋性或抑制性化学突触耦合的基于映射的神经元组成的系统。在简要解释了脉冲产生和同步背后的基本机制之后，探索参数空间以确定不太明显但具有生物学意义的状态和效应。其中，我们展示了没有任何延迟的兴奋性突触如何诱导反相同步；一个突触如何通过改变其电导而改变其性质，从兴奋性变为抑制性，反之亦然，而反转电位没有任何变化；以及突触阈值的微小变化如何导致脉冲内尖峰同步的剧烈变化。最后，我们展示了在双神经元系统中发现的同步效应如何扩展到更大的网络。
