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普通人群中职业性粉尘或气体暴露与呼吸道症状及哮喘患病率的关系

Occupational dust or gas exposure and prevalences of respiratory symptoms and asthma in a general population.

作者信息

Bakke P, Eide G E, Hanoa R, Gulsvik A

机构信息

Dept of Thoracic Medicine, University of Bergen, Norway.

出版信息

Eur Respir J. 1991 Mar;4(3):273-8.

PMID:1864342
Abstract

The relationship of occupational airborne, exposure to respiratory symptoms and asthma was examined using a self-administered questionnaire in a cross-sectional survey of a random sample (n = 4,992 subjects) of the general population aged 15-70 yrs of Hordaland county, Norway. The response rate was 90%. Twenty nine percent of the population had a history of occupational dust or gas exposure, 5% reported having been exposed to asbestos at work, and 4% reported quartz exposure. A history of occupational dust or gas exposure was associated with morning cough, chronic cough, phlegm when coughing, breathlessness on exercise, occasional wheezing and a physician's diagnosis of asthma after adjusting for sex, age, smoking habits and urban-rural area of residence. The adjusted relative odds ratios for the respiratory disorders in subjects exposed to dust or gas ranged from 1.6-1.9. The population attributable risk of occupational dust or gas exposure for the respiratory disorders ranged from 11-19%. The study indicates that respiratory disorders are independently associated with occupational airborne exposure in a Norwegian general population sample.

摘要

在挪威霍达兰郡对15 - 70岁普通人群的随机样本(n = 4992名受试者)进行的横断面调查中,使用自行填写的问卷研究了职业性空气传播暴露与呼吸道症状及哮喘之间的关系。应答率为90%。29%的人群有职业性粉尘或气体暴露史,5%报告曾在工作中接触石棉,4%报告有石英暴露史。在调整了性别、年龄、吸烟习惯和城乡居住区域后,职业性粉尘或气体暴露史与晨咳、慢性咳嗽、咳嗽时有痰、运动时气短、偶尔喘息以及医生诊断的哮喘有关。暴露于粉尘或气体的受试者中,呼吸道疾病的调整后相对比值比在1.6 - 1.9之间。职业性粉尘或气体暴露对呼吸道疾病的人群归因风险在11% - 19%之间。该研究表明,在挪威普通人群样本中,呼吸道疾病与职业性空气传播暴露独立相关。

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