日本既往乙肝病毒感染已缓解患者中暴发性肝衰竭所致的死亡率
Mortality secondary to fulminant hepatic failure in patients with prior resolution of hepatitis B virus infection in Japan.
作者信息
Umemura Takeji, Tanaka Eiji, Kiyosawa Kendo, Kumada Hiromitsu
机构信息
Department of Internal Medicine, Hepatology, and Gastroenterology, Shinshu University School of Medicine, Matsumoto, Japan.
出版信息
Clin Infect Dis. 2008 Sep 1;47(5):e52-6. doi: 10.1086/590968.
DOI:10.1086/590968
PMID:18643758
Abstract
Hepatitis B virus (HBV) reactivation in patients with resolved HBV infection was found in 23 (4%) of 552 newly hepatitis B surface antigen-positive patients in Japan. Because one-fourth of cases develop into fulminant hepatic failure and mortality is 100%, management of HBV reactivation in patients with resolved HBV infection should be discussed.
摘要
在日本，552例新出现乙肝表面抗原阳性的患者中，有23例（4%）被发现存在乙肝病毒（HBV）感染已缓解患者的HBV再激活情况。由于四分之一的病例会发展为暴发性肝衰竭且死亡率为100%，因此应讨论对HBV感染已缓解患者的HBV再激活的管理。
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