Lauvao Lannery S, Goshima Kaoru R, Leon Luis R, Nolan Paul E, Hughes John D
University of Arizona Health Science Center and Southern Arizona Veterans Affairs Health Care System, Tucson, Ariz, USA.
J Vasc Surg. 2008 Aug;48(2):472-7. doi: 10.1016/j.jvs.2008.02.052.
Antiphospholipid syndrome is a diagnosis with the clinical manifestations of thromboses in the presence of an antiphospholipid antibody. A 25-year-old man with a history of deep venous thrombosis, pulmonary emboli, and myocardial infarction, and receiving long-term anticoagulation with warfarin, all due to primary antiphospholipid syndrome, presented with blue toe syndrome from a primary superficial femoral artery thrombus. He was anticoagulated with fondaparinux in addition to dipyridamole and aspirin perioperatively. The area of thrombus was resected and reconstructed using a cephalic vein interposition graft. This report reviews antiphospholipid syndrome and identifies potential questions and problems relating to a rare clinical presentation.
抗磷脂综合征是一种在存在抗磷脂抗体时具有血栓形成临床表现的诊断。一名25岁男性，有深静脉血栓形成、肺栓塞和心肌梗死病史，因原发性抗磷脂综合征长期接受华法林抗凝治疗，现因原发性股浅动脉血栓形成出现蓝趾综合征。他在围手术期除接受双嘧达莫和阿司匹林治疗外，还使用磺达肝癸钠进行抗凝。血栓区域被切除，并使用头静脉间置移植物进行重建。本报告回顾了抗磷脂综合征，并确定了与这种罕见临床表现相关的潜在问题。
