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非肝硬化性门静脉高压症中的IgA肾病

IgA nephropathy in non-cirrhotic portal hypertension.

作者信息

Babbs C, Warnes T W, Torrance H B, Ballardie F W

机构信息

University Department of Gastroenterology Manchester Royal Infirmary.

出版信息

Gut. 1991 Feb;32(2):225-6. doi: 10.1136/gut.32.2.225.

Abstract

Renal glomerular changes are a well recognised complication of cirrhosis and are frequently characterised by mesangial IgA deposition. We report a patient with non-cirrhotic portal hypertension who developed IgA nephropathy and a nephrotic syndrome with renal histological changes classically associated with cirrhosis. Splenectomy with resection of a splenic artery aneurysm resulted in remission of the nephrotic syndrome. This case illustrates the factors which contribute to the pathogenesis of IgA nephropathy in liver disease.

摘要

肾小球改变是肝硬化一种公认的并发症,常表现为系膜IgA沉积。我们报告一例非肝硬化性门静脉高压患者,该患者发生了IgA肾病及肾病综合征,其肾脏组织学改变通常与肝硬化相关。脾切除并切除脾动脉动脉瘤后,肾病综合征缓解。该病例说明了肝病中导致IgA肾病发病机制的因素。

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Immunologic studies in IgA nephropathy.IgA肾病的免疫学研究。
Kidney Int. 1980 Sep;18(3):366-74. doi: 10.1038/ki.1980.147.
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Heterogeneous IgA glomerulonephropathy in liver cirrhosis.肝硬化中的异质性IgA肾小球肾炎
Histopathology. 1984 Nov;8(6):947-62. doi: 10.1111/j.1365-2559.1984.tb02413.x.

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