内化问题的代际传递：父母及祖父母的重度抑郁症对儿童行为的影响。
Intergenerational transmission of internalizing problems: effects of parental and grandparental major depressive disorder on child behavior.
作者信息
Pettit Jeremy W, Olino Thomas M, Roberts Robert E, Seeley John R, Lewinsohn Peter M
机构信息
Department of Psychology, University of Houston, Houston, TX 77204-5022, USA.
出版信息
J Clin Child Adolesc Psychol. 2008 Jul;37(3):640-50. doi: 10.1080/15374410802148129.
Abstract
Effects of lifetime histories of grandparental (G1) and parental (G2) major depressive disorder (MDD) on children's (G3) internalizing problems were investigated among 267 G3 children (ages 2-18 years) who received Child Behavior Checklist (CBCL) ratings and had diagnostic data available on 267 biological G2 parents and 527 biological G1 grandparents. Results indicated that G1 MDD conferred risk for G2 MDD, but not for G3 CBCL scores. G2 MDD predicted higher G3 Internalizing and Anxious/Depressed scores. Also, there was an interaction between G1 MDD and G2 MDD in predicting higher G3 Anxious/Depressed scores such that scores were highest among children with both depressed parents and grandparents. These effects were robust to statistical adjustments for status variables and parental relationship measures but not to adjustment for concurrent parental depressive symptoms.
摘要
在267名接受儿童行为检查表（CBCL）评分且有267名亲生G2代父母和527名亲生G1代祖父母诊断数据的G3代儿童（2至18岁）中，研究了祖父母（G1）和父母（G2）的重度抑郁症（MDD）终生病史对儿童（G3）内化问题的影响。结果表明，G1代MDD会增加G2代患MDD的风险，但不会影响G3代的CBCL评分。G2代MDD预示着G3代有更高的内化及焦虑/抑郁评分。此外，在预测G3代更高的焦虑/抑郁评分方面，G1代MDD和G2代MDD之间存在交互作用，即父母和祖父母均患抑郁症的儿童得分最高。这些效应在对状态变量和父母关系测量进行统计调整后依然稳健，但在对同时存在的父母抑郁症状进行调整时则不然。
相似文献
1
Intergenerational transmission of internalizing problems: effects of parental and grandparental major depressive disorder on child behavior.内化问题的代际传递：父母及祖父母的重度抑郁症对儿童行为的影响。
J Clin Child Adolesc Psychol. 2008 Jul;37(3):640-50. doi: 10.1080/15374410802148129.
2
Influence of parental and grandparental major depressive disorder on behavior problems in early childhood: a three-generation study.父母及祖父母的重度抑郁症对幼儿行为问题的影响：一项三代人研究。
J Am Acad Child Adolesc Psychiatry. 2008 Jan;47(1):53-60. doi: 10.1097/chi.0b013e31815a6ae6.
3
Influences of biological and adoptive mothers' depression and antisocial behavior on adoptees' early behavior trajectories.生物母亲和养母的抑郁和反社会行为对被收养者早期行为轨迹的影响。
J Abnorm Child Psychol. 2013 Jul;41(5):723-34. doi: 10.1007/s10802-013-9711-6.
4
Grandparents, parents, and grandchildren at high risk for depression: a three-generation study.抑郁症高危人群中的祖父母、父母和孙辈：一项三代人研究。
J Am Acad Child Adolesc Psychiatry. 1999 Mar;38(3):289-96. doi: 10.1097/00004583-199903000-00016.
5
Screening parents during child evaluations: exploring parent and child psychopathology in the same clinic.在儿童评估中对父母进行筛查：在同一家诊所中探索父母和儿童的精神病理学。
J Am Acad Child Adolesc Psychiatry. 2011 May;50(5):441-50. doi: 10.1016/j.jaac.2011.02.002. Epub 2011 Apr 5.
6
The impact of parental borderline personality disorder on vulnerability to depression in children of affectively ill parents.父母边缘型人格障碍对情感疾病患者子女患抑郁症易感性的影响。
J Pers Disord. 2005 Feb;19(1):68-83. doi: 10.1521/pedi.19.1.68.62177.
7
Major depressive disorder in adolescents: family psychiatric history predicts severe behavioral disinhibition.青少年重度抑郁症：家族精神病史预示着严重的行为抑制障碍。
J Affect Disord. 2006 Feb;90(2-3):111-21. doi: 10.1016/j.jad.2005.09.011. Epub 2005 Dec 13.
8
Families at high and low risk for depression: a 3-generation study.抑郁症高风险和低风险家庭：一项三代人的研究。
Arch Gen Psychiatry. 2005 Jan;62(1):29-36. doi: 10.1001/archpsyc.62.1.29.
9
The role of fear and anxiety in the familial risk for major depression: a three-generation study.恐惧和焦虑在重度抑郁症家族风险中的作用：一项三代人的研究。
Psychol Med. 2008 Nov;38(11):1543-56. doi: 10.1017/S0033291708002894. Epub 2008 Feb 14.
10
A 30-Year Study of 3 Generations at High Risk and Low Risk for Depression.一项针对抑郁症高风险和低风险三代人的30年研究。
JAMA Psychiatry. 2016 Sep 1;73(9):970-7. doi: 10.1001/jamapsychiatry.2016.1586.
引用本文的文献
1
Intergenerational Parenting Styles and Children's Problem Behaviors: The Mediating Role of the Grandparent-Parent Relationship.代际育儿方式与儿童问题行为：祖孙亲子关系的中介作用
Behav Sci (Basel). 2025 Jul 29;15(8):1029. doi: 10.3390/bs15081029.
2
Parental depressive symptoms and child psychopathology: Indirect effects of parenting-specific emotion regulation and emotion socialization.父母的抑郁症状与儿童精神病理学：特定养育方式下情绪调节和情绪社会化的间接影响。
Fam Relat. 2025 Feb;74(1):481-499. doi: 10.1111/fare.13095. Epub 2024 Nov 3.
3
Polygenic scores for psychiatric traits mediate the impact of multigenerational history for depression on offspring psychopathology.精神疾病性状的多基因分数介导了抑郁症的多代病史对后代精神病理学的影响。
Res Sq. 2024 Jul 17:rs.3.rs-4264742. doi: 10.21203/rs.3.rs-4264742/v1.
4
Subcortical volumes in offspring with a multigenerational family history of depression - A study across two cohorts.有跨代家族抑郁史的后代的皮质下体积 - 两个队列的研究。
J Affect Disord. 2024 Oct 15;363:192-197. doi: 10.1016/j.jad.2024.07.107. Epub 2024 Jul 17.
5
Early emotional caregiving environment and associations with memory performance and hippocampal volume in adolescents with prenatal drug exposure.早期情感照料环境及其与产前药物暴露青少年记忆表现和海马体体积的关联。
Front Behav Neurosci. 2023 Nov 20;17:1238172. doi: 10.3389/fnbeh.2023.1238172. eCollection 2023.
6
The Relationship Between Parenting Styles Practiced By Grandparents And Children's Emotional And Behavioral Problems.祖父母养育方式与儿童情绪及行为问题之间的关系
J Child Fam Stud. 2019 Jul;28(7):1899-1913. doi: 10.1007/s10826-019-01415-7. Epub 2019 May 22.
7
The Impact of Personality Pathology Across Three Generations: Evidence from the St. Louis Personality and Intergenerational Network Study.三代人个性病理学的影响：来自圣路易斯个性与代际网络研究的证据。
Clin Psychol Sci. 2021 Sep;9(5):900-918. doi: 10.1177/2167702621989665. Epub 2021 Apr 5.
8
Enduring problems in the offspring of depressed parents followed up to 38 years.对抑郁父母的后代长达38年的持续性问题进行随访。
EClinicalMedicine. 2021 Jul 13;38:101000. doi: 10.1016/j.eclinm.2021.101000. eCollection 2021 Aug.
9
Trajectories of Depressive Symptoms Among North American Indigenous Adolescents: Considering Predictors and Outcomes.北美原住民青少年抑郁症状轨迹：考虑预测因素和结果。
Child Dev. 2020 May;91(3):932-948. doi: 10.1111/cdev.13268. Epub 2019 Jul 31.
10
Parental Divorce, Familial Risk for Depression, and Psychopathology in Offspring: A Three-Generation Study.父母离异、子女患抑郁症的家族风险及精神病理学：一项三代人研究
J Child Fam Stud. 2012 Oct;21(5):718-725. doi: 10.1007/s10826-011-9523-7. Epub 2011 Sep 4.
本文引用的文献
1
Risk factors for preschool depression: the mediating role of early stressful life events.学龄前儿童抑郁症的风险因素：早期应激性生活事件的中介作用。
J Child Psychol Psychiatry. 2006 Dec;47(12):1292-8. doi: 10.1111/j.1469-7610.2006.01672.x.
2
The developmental origins of cognitive vulnerability to depression: temperament, parenting, and negative life events in childhood as contributors to negative cognitive style.抑郁症认知易感性的发展起源：气质、养育方式及童年期负面生活事件作为负面认知风格的影响因素
Dev Psychol. 2006 Nov;42(6):1012-25. doi: 10.1037/0012-1649.42.6.1012.
3
Linking substance use and problem behavior across three generations.三代人物质使用与问题行为的关联
J Abnorm Child Psychol. 2006 Jun;34(3):263-92. doi: 10.1007/s10802-006-9033-z. Epub 2006 Jun 3.
4
Prevalence and genetic and environmental influences on anxiety disorders in 6-year-old twins.6岁双胞胎焦虑症的患病率及其遗传和环境影响
Psychol Med. 2006 Mar;36(3):335-44. doi: 10.1017/S0033291705006537. Epub 2005 Nov 17.
5
Genetic and environmental influences on Anxious/Depression during childhood: a study from the Netherlands Twin Register.童年期焦虑/抑郁的遗传和环境影响：来自荷兰双胞胎登记处的一项研究
Genes Brain Behav. 2005 Nov;4(8):466-81. doi: 10.1111/j.1601-183X.2005.00141.x.
6
Discriminant validity and clinical utility of the CBCL with anxiety-disordered youth.《儿童行为检查表》对焦虑症青少年的区分效度及临床实用性
J Clin Child Adolesc Psychol. 2005 Dec;34(4):735-46. doi: 10.1207/s15374424jccp3404_15.
7
Association of parental depression with psychiatric course from adolescence to young adulthood among formerly depressed individuals.曾患抑郁症个体中父母抑郁与从青少年期到青年期精神疾病病程的关联。
J Abnorm Psychol. 2005 Aug;114(3):409-20. doi: 10.1037/0021-843X.114.3.409.
8
The apple does not fall far from the tree: attachment styles and personality vulnerabilities to depression in three generations of women.有其父必有其子：三代女性的依恋风格与易患抑郁症的人格特质
Pers Soc Psychol Bull. 2005 Aug;31(8):1052-73. doi: 10.1177/0146167204274082.
9
Towards a family process model of maternal and paternal depressive symptoms: exploring multiple relations with child and family functioning.迈向父母抑郁症状的家庭过程模型：探索与儿童及家庭功能的多重关系。
J Child Psychol Psychiatry. 2005 May;46(5):479-89. doi: 10.1111/j.1469-7610.2004.00368.x.
10
Psychopathology in the adolescent and young adult offspring of a community sample of mothers and fathers with major depression.患有重度抑郁症的社区样本父母的青少年及年轻成年子女的精神病理学
Psychol Med. 2005 Mar;35(3):353-65. doi: 10.1017/s0033291704003587.
Zotero 插件