赖氨酸酰胺衍生物的生物活性。
Biological activity of amide derivatives of lysine.
作者信息
Midura-Nowaczek Krystyna, Lepietuszko Izabela, Bruzgo Irena, Markowska Agnieszka
机构信息
Department of Organic Chemistry, Medical University of Białystok, Białystok, Poland.
出版信息
Acta Pol Pharm. 2008 May-Jun;65(3):377-81.
PMID:18646558
Abstract
Five substituted amides of lysine with the general formula: X-Lys-NH-Y, where X= acetyl or ethoxycarbonyl, Y= cyclohexyl, benzyl, hexyl or cadaverine residue were synthesised and their effects on fibrinolytic activity of plasmin, clotting activity of thrombin and amidolytic activities of both enzymes were examined.
摘要
合成了通式为X-Lys-NH-Y的5种赖氨酸取代酰胺，其中X = 乙酰基或乙氧羰基，Y = 环己基、苄基、己基或尸胺残基，并检测了它们对纤溶酶的纤维蛋白溶解活性、凝血酶的凝血活性以及两种酶的酰胺水解活性的影响。
Zotero 插件