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Synthesis of alkylamides of dipeptides as potential plasmin inhibitors.

作者信息

Midura-Nowaczek Krystyna, Lepietuszko Izabela, Bruzgo Irena

机构信息

Department of Organic Chemistry, Medical University of Białystok, 1 Kilińskiego Str., 15-089 Białystok, Poland.

出版信息

Acta Pol Pharm. 2006 Jan-Feb;63(1):33-7.

Abstract

Four dipeptide alkylamides with general formula H-D-Phe-L-Lys-NH-X, where X = cyclohexyl, - (CH2)5NH2, -(CH2)2-OH and hexyl were obtained. Effect of these compounds on amidolytic and fibrinolytic activity of plasmin was examined.

摘要

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