Rao V M, Sebes J I, Steiner R M, Ballas S K
Jefferson Medical College, Thomas Jefferson University, Philadelphia, Pennsylvania.
Hematol Oncol Clin North Am. 1991 Jun;5(3):517-33.
We have provided a global review of the current applications of newer modalities, particularly MR imaging, as applicable to the major manifestations of sickle cell disease, the most common hemoglobinopathy. There is a need for well-designed prospective longitudinal studies utilizing MR imaging to gain further insight into the pathophysiology of this intriguing disease. Additionally, MR imaging, because of lack of ionizing radiation, is ideally suited for long-term sequential studies and may thus provide an objective means for monitoring response to therapy.
我们对适用于镰状细胞病（最常见的血红蛋白病）主要表现的更新技术，尤其是磁共振成像（MR成像）的当前应用进行了全面综述。需要开展精心设计的前瞻性纵向研究，利用MR成像进一步深入了解这种有趣疾病的病理生理学。此外，由于MR成像不存在电离辐射，非常适合进行长期的连续研究，因此可能为监测治疗反应提供一种客观手段。
