Andhavarapu Swati, Tolentino Arturo M, Jha Chandra, Ravi Jyotsna, Carlson Richard, Nair Geetha R
Department of Internal Medicine, Maricopa Medical Center, Phoenix, AZ 85008, USA.
Clin Lymphoma Myeloma. 2008 Jun;8(3):179-83. doi: 10.3816/CLM.2008.n.023.
Primary gastrointestinal (GI) lymphomas constitute 5%-10% of all gastrointestinal tumors. Involvement of the entire GI tract as multiple polypoid lesions is very rare. Multiple lymphomatous polyposis is a distinctive and rare type of malignant GI lymphoma. Multiple lymphomatous polyposis is thought to represent mantle cell lymphoma of the GI tract. Approximately 60 cases of MLP have been reported so far. We report the first case of diffuse large B-cell lymphoma presenting as multiple lymphomatous polyposis of the GI tract in a 49-year-old patient with HIV and describe the clinicopathologic features. The patient was treated with a combination therapy of highly active antiretroviral therapy and CHOP (cyclophosphamide/doxorubicin/vincristine/prednisone) and exhibited complete remission.
原发性胃肠道淋巴瘤占所有胃肠道肿瘤的5%-10%。整个胃肠道以多发息肉样病变受累极为罕见。多发性淋巴瘤性息肉病是一种独特且罕见的恶性胃肠道淋巴瘤类型。多发性淋巴瘤性息肉病被认为代表胃肠道的套细胞淋巴瘤。迄今为止，已报道约60例多发性淋巴瘤性息肉病。我们报告首例表现为胃肠道多发性淋巴瘤性息肉病的弥漫性大B细胞淋巴瘤病例，该患者为一名49岁的艾滋病患者，并描述其临床病理特征。该患者接受了高效抗逆转录病毒疗法与CHOP（环磷酰胺/阿霉素/长春新碱/泼尼松）联合治疗，实现了完全缓解。
