多发性硬化症中的大细胞性贫血。对82例初发阿拉伯患者的研究。
Macrocytosis in multiple sclerosis. A study in 82 de novo Arab patients.
作者信息
Najim al-Din A S, Khojali M, Habbosh H, Farah S, Idris A R, al-Muhtasib F
机构信息
Department of Medicine, Faculty of Medicine, Kuwait University.
出版信息
J Neurol Neurosurg Psychiatry. 1991 May;54(5):415-6. doi: 10.1136/jnnp.54.5.415.
Abstract
Macrocytosis, without anaemia, was common in 82 de novo multiple sclerosis patients compared with a similar number of age and sex matched controls. This was an early phenomenon in the course of the disease and was not influenced by the age of the patients nor the duration of the disease. None of the patients proved to have pernicious anaemia, yet the similarity in the geographical and sex distribution as well as the similarity in HLA associations of multiple sclerosis and pernicious anaemia may indicate that both diseases are under similar genetic influence.
摘要
在82例初发多发性硬化症患者中，无贫血的大细胞血症很常见，与之相比，有数量相近的年龄和性别匹配的对照组。这是疾病过程中的早期现象，不受患者年龄和病程的影响。没有患者被证实患有恶性贫血，然而，多发性硬化症和恶性贫血在地理分布和性别分布上的相似性以及HLA关联的相似性可能表明这两种疾病受相似的遗传影响。
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本文引用的文献
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