Eliseev M S, Barskova V G
Vestn Ross Akad Med Nauk. 2008(6):29-32.
The presence of metabolic syndrome (MS) is characteristic for many patients with gout. MS is closely associated with a generalized disorder called insulin resistance (IR) or impaired tissue responsiveness to the normal action in insulin. MS and IR define cardiovascular disease risks and are the main factors leading to severe disease associated with chronic arthritis and struck joints in gout patients. Given serious complications associated with MS, this frequent comorbidity should be recognized and be taken into account in the long-term treatment and overall health of individuals with gout. The review is devoted to studying MS and IR in gout patients.
代谢综合征(MS)的存在是许多痛风患者的特征。MS与一种称为胰岛素抵抗(IR)或组织对胰岛素正常作用的反应性受损的全身性疾病密切相关。MS和IR决定了心血管疾病风险,并且是导致痛风患者慢性关节炎和关节疼痛等严重疾病的主要因素。鉴于与MS相关的严重并发症,这种常见的合并症在痛风患者的长期治疗和整体健康中应得到认识并加以考虑。这篇综述致力于研究痛风患者的MS和IR。