Voronezhskaya Elena E, Glebov K I, Khabarova Marina Yu, Ponimaskin E G, Nezlin L P
Department of Comparative Physiology, Institute for Developmental Biology, Moscow, Russia.
Acta Biol Hung. 2008;59 Suppl:117-22. doi: 10.1556/ABiol.59.2008.Suppl.19.
The regulation of larval development by starved adults occurs in both freshwater snails, Helisoma trivolvis and marine polychaetes, Platynereis dumerilii. Serotonin (5-HT) links this environmental signal which is detected by larval apical sensory neurons to changes in larval development. A profile of the stage-dependent expression of 5-HT receptors and coupled G proteins is essential in this regulatory mechanism. The final effect on development depends on the modulation of the activity of the larval digestive system.
饥饿的成年个体对幼虫发育的调控在淡水蜗牛（三角帆蚌）和海洋多毛类动物（杜氏阔沙蚕）中均有发生。血清素（5-羟色胺，5-HT）将幼虫顶端感觉神经元检测到的这种环境信号与幼虫发育的变化联系起来。5-HT受体和偶联G蛋白的阶段依赖性表达谱在这一调控机制中至关重要。对发育的最终影响取决于幼虫消化系统活性的调节。
